
This landing page contains reference links to the information in the video.
1) Failure to recognize/respond to deterioration (“failure to rescue”; ~10–13% estimate)
• McGrath SP, Blike G, Gale BM, Mossburg SE. Surveillance Monitoring to Improve Patient Safety in Acute Hospital Care Units. PSNet (AHRQ). Published Apr 26, 2023.
• Hairon N. Improving response to signs of patient deterioration (reports NPSA analysis: >11% of 576 deaths related to deterioration not recognised / not acted on). Nursing Times. Nov 27, 2007.
2) General-ward monitoring gaps (vital signs often every 4–8 hours)
• McGrath SP, Blike G, Gale BM, Mossburg SE. Surveillance Monitoring to Improve Patient Safety in Acute Hospital Care Units. PSNet (AHRQ). Apr 26, 2023.
• Khanna AK, Flick M, Saugel B. Continuous vital sign monitoring of patients recovering from surgery on general wards: a narrative review. British Journal of Anaesthesia. 2025
3) Deterioration commonly precedes major events by hours (supports “deterioration happens in those gaps”)
• Schein RMH, Hazday N, Pena M, Ruben BH, Sprung CL. Clinical antecedents to in-hospital cardiopulmonary arrest. CHEST. 1990;98(6):1388–1392.
• Andersen LW, Kim WY, Chase M, et al. The prevalence and significance of abnormal vital signs prior to in-hospital cardiac arrest. Resuscitation. 2016;98:112–117.
4) STEMI: mortality increases with treatment delay (30-minute increments)
• De Luca G, Suryapranata H, Ottervanger JP, Antman EM. Time delay to treatment and mortality in primary angioplasty for acute myocardial infarction: every minute of delay counts. Circulation. 2004;109(10):1223–1225
5) Postoperative deaths after discharge (~29% of 30-day deaths)
• VISION Study Investigators (Spence J, LeManach Y, Chan MTV, et al.). Association between complications and death within 30 days after noncardiac surgery. CMAJ. 2019;191(30):E830–E837.
6) In-flight medical emergencies (~60,000/year; derived estimate)
• Peterson DC, Martin-Gill C, Guyette FX, et al. Outcomes of medical emergencies on commercial airline flights. New England Journal of Medicine. 2013;368(22):2075–2083.
• International Civil Aviation Organization (ICAO). The World of Air Transport in 2023 (reports ~35.3 million departures in 2023).
NOTE ON THE “~60,000 IN-FLIGHT MEDICAL EMERGENCIES/YEAR” FIGURE:
Using NEJM’s estimate (~1 medical
emergency per 604 flights) and
ICAO’s 35.3 million annual
departures:
35.3M / 604 ≈
58,000 (60,000) in-flight medical emergencies per year (order-of-magnitude estimate).